Deadline: 1 December 2017
Senior Lecturer/ Reader – Structural Biology
Cardiff School of Biosciences
Teaching & Research
Senior Lecturer/ Reader – Structural Biology
The newly-established Medicines Discovery Institute represents a major investment in translational science by Cardiff University. The goal of the Institute is to translate world-leading research on scientific understanding of disease mechanisms into innovative therapeutic approaches. Our vision is to play a leading role in discovering new medicines in areas of high unmet need, with a particular emphasis on, but not exclusive to, neuroscience and mental health. We are creating a vibrant community of researchers across both academic and biotech sectors engaged in major research programmes which build off the unique strengths of Cardiff University and work collaboratively with other universities and companies across Wales and internationally.
Building off investment from both the European Regional Development Fund through the Welsh Government’s Sêr Cymru scheme and Cardiff University, we will recruit a number of key academic, research and operational roles to work alongside the current and future grant & industry funded staff. This recruitment will take place over 2017-2018.
We are currently looking for three faculty positions to support the lead academics, the Sêr Cymru Professors in Translational Drug Discovery, Profs John Atack and Simon Ward, in the Medicines Discovery Institute. These new faculty positions will cover expertise in assay development, cell biology and structural biology and interface with the existing experience in translational neuroscience and medicinal chemistry. These tenured, academic posts will play a key role in developing and supporting a portfolio of major translational drug discovery projects and will be critical to the success of the Medicines Discovery Institute and the building of a cohesive, inter-dependent working environment. As such, it is expected that the main research interests of all five faculty positions are well aligned and the successful applicants will be required to demonstrate successful team working and established or emerging excellence within the relevant field.
We seek to appoint a talented, enthusiastic structural biologist who has internationally recognised expertise in the fields of protein crystallography and structure-based drug discovery. This individual will play a key role in building capability in protein production, crystallography and structure-based drug discovery and in establishing effective links to key external networks, such as SGC, Diamond Light Source etc. This person will have a solid track record of structure-based drug discovery from an academic or pharmaceutical company background and will work to initiate and prosecute a portfolio of structurally-enabled drug discovery targets.
To deliver high-quality teaching and research, leading to the publishing of work in high-quality journals and/or the generation of drug discovery-related Intellectual Property. To pursue excellence in research and teaching , training and enterprise and to inspire others to do the same.
This post is full time and open ended.
Salary: £49,149 – £56,950 per annum (Grade 8)
Date post advertised: Tuesday, 31 October 2017
Closing date: Friday, 1 December 2017
Please be aware that Cardiff University reserves the right to close this vacancy early should sufficient applications be received. Cardiff University is committed to supporting and promoting equality and diversity and to creating an inclusive working environment. We believe this can be achieved through attracting, developing, and retaining a diverse range of staff from many different backgrounds who have the ambition to create a University which seeks to fulfil our social, cultural and economic obligation to Cardiff, Wales, and the world. In supporting our employees to achieve a balance between their work and their personal lives, we will also consider proposals for flexible working or job share arrangements.
To deliver high-quality and research-led teaching at both undergraduate and postgraduate level and contribute to the research record of the School through commitment to carrying out research leading to the publishing of work in high-quality journals. To pursue excellence in research, teaching and enterprise and to inspire others to do the same.
• To conduct research within the field of Structural Biology and contribute to the overall internationally recognised research performance of the School and its Research Institutes by the production of measurable outputs including bidding for funding, contribution to the generation of Intellectual Property (i.e., patents), publishing in leading international academic journals and high-impact conferences, and the recruitment and supervision of research staff and postgraduate research students
• To contribute to and/or lead successful bids for funding
• To give invited addresses to professional meetings and conferences at national and international level, building networks to develop research outputs and standing within the area of specialism to participate in School research activities
• To contribute fully to the management of postgraduate and postdoctoral research
• To lead on degree and module development and delivery and contribute to the pedagogy of subject area
• To act as programme manager, module leader and / or tutor – ensuring delivery of teaching in line with current curricular requirements, developing and applying innovative and appropriate teaching techniques and material which create interest, understanding and enthusiasm amongst students
• To undertake work associated with examinations, such as setting and marking assessments and providing student feedback
• To act as a Personal Tutor and provide pastoral support to students, including supervising the work of Undergraduate and Master’s students, the co-supervision of PGR’s and acting as a PGR progress review panel member as required
• To be involved in the departmental level strategic planning and contribute to wider strategic planning processes in the University
• Develop strategic academic and/or industrial partnerships both within and external to the University
• To undertake and lead operational administrative responsibilities as requested by Head of School and senior management team, and contribute to and/or lead bids for consultancy and additional funds
• To engage effectively with industrial, commercial and public sector organisations, professional institutions, other academic institutions etc., regionally and nationally and internationally to raise awareness of the School’s profile, to cultivate strategically valuable alliances, and to pursue opportunities for collaboration across a range of activities. These activities are expected to contribute to the School and the enhancement of its regional, national, and international profile.
• Any other duties not included above, but consistent with the role.
Qualifications and Education
1. Postgraduate degree at PhD level in a related subject area including industrial drug discovery experience within a multinational pharmaceutical company
Knowledge, Skills and Experience
2. A well-established expertise and significant proven portfolio of research and/or relevant industrial experience within the following research fields:
Recombinant protein construct design
Structure-based drug discovery
Biophysical assay methodology
3. Established national and growing international reputation within the structural biology community
4. Proven substantial record of publications in high-impact national and international journals.
5. Familiarity with different strategies for structure-based drug discovery (e.g., screening strategies based around X-ray crystallography, NMR, SPR)
6. Proven experience within the area of structure-based ion channel drug discovery within the neuroscience therapeutic area
7. Substantial teaching experience at undergraduate/postgraduate level, demonstrating teaching innovation and course development and design, providing appropriate pastoral support to students, appreciate the needs of individual students and their circumstances and to act as a personal tutor
8. Proven ability to design, deliver and continuously develop modules across the Schools teaching programmes
Pastoral, Communication and Team Working
9. Evidence of ability to work within a team across functional groups (e.g., biologists and medicinal chemists)
10. Evidence of supervision and management of postgraduate and postdoctoral scientists
1. Relevant professional qualification(s).
2. Evidence of collaborations with academia while in Industry
Salary Range Min.
Salary Range Max.
Academic – Teaching & Research