Postdoctoral Research Associate in Chromatin-mediated silencing of endogenous human retroelements, UK

University of Cambridge
Postdoc Research
Study in:UK
Deadline: 6 February 2018

Postdoctoral Research Associate in Chromatin-mediated silencing of endogenous human retroelements

Applications are invited for an enthusiastic, motivated individual for a Wellcome Trust funded postdoctoral position in the group of Professor Paul Lehner at the Cambridge Institute for Medical Research on the Cambridge Biomedical Campus, University of Cambridge .

You will join an exciting research programme using genetic and proteomic approaches to understand chromatin-mediated silencing of endogenous human retroelements, with specific reference to the novel HUSH epigenetic transcriptional repressor complex (Tchasovnikarova IA et al Science (2015) 348:1481-5, Nature Genetics (2017) 49:1035-1044, et Liu al Nature Dec 6 (2017)) which is responsible for chromatin-mediated repression of cellular transgenes and newly integrated retroviruses.

This post will involve the use of cutting edge genetic, biochemical, proteomic and bioinformatic techniques to study mechanisms of retroviral silencing. Candidates should have a PhD with experience in virology or chromatin biology, in chromatin biochemistry and cell biological techniques. Quantitative and analytical skills, as well as expertise in bioinformatics are also desirable. If you have an excellent background in biological sciences, have published in high impact journals, are prepared to face intellectual challenges and wish to develop your scientific skills, we would like to hear from you.

Applicants should have excellent organisation and communication skills, and work well as part of a team.

Fixed-term: The funds for this post are available for 3 years in the first instance with an immediate start date.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the ‘Apply’ button below. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

For further details or informal enquires please contact Paul Lehner via email ( .

Please quote reference SC14458 on your application and in any correspondence about this vacancy.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information

Apply online

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