Deadline: 31 January 2018
Postdoctoral Researcher: Chromatin Biology Cellular Differentiation (0.8 – 1.0 FTE)
Faculty of Science
Maximum salary: € 4,084 gross/month
Vacancy number: 62.98.17
Application deadline: 31 January 2018
This ambitious project will address the molecular epigenetic basis of cellular identity. The Polycomb group of proteins are important regulators of this identity as these proteins repress ectopic expression of developmental control genes. This controls proliferation, patterning and cell-lineage commitment and is deregulated in cancer. How Polycomb is targeted to genes in humans and other vertebrates has remained enigmatic for a long time, but our recent results have shed exciting new light on this issue: we have identified a protein that directs Polycomb to its target genes by direct binding of unmethylated DNA.
As a postdoctoral researcher you will further elucidate how Polycomb controls gene regulation. Using state-of-the-art molecular techniques (next-generation sequencing, mass spectrometry) you will examine how Polycomb recruitment is regulated during cellular differentiation and in malignancies. You will have the opportunity to develop and work on novel ideas.
We are looking for a highly motivated and ambitious experimental biologist to join our research team in the Department of Molecular Developmental Biology, located at the Radboud Institute for Molecular Life Sciences (RIMLS), Faculty of Science (Radboud University, Nijmegen, Netherlands). We offer a first class international research environment in regulation of gene expression and epigenetics using state-of-the-art genomic and proteomic technologies and bioinformatics. We run next-generation sequencers, single-cell equipment, and mass spectrometers, and we accommodate a bioinformatics team and a local computational infrastructure.
What we expect from you
- a PhD in molecular or cellular biology, molecular life sciences or a related field;
- experience in one or more of the following areas: molecular biology techniques, next-generation sequencing, genomics and gene regulation, or computational analysis;
- excellent communication skills in written and spoken English;
- strong analytical skills, a problem-solving and result-oriented attitude;
- the ability to work and interact with others in an energetic and supportive research environment.
What we have to offer
- employment: 0.8 – 1.0 FTE;
- a maximum gross monthly salary of € 4,084 based on a 38-hour working week (salary scale 10);
- in addition to the salary: an 8% holiday allowance and an 8.3% end-of-year bonus;
- duration of the contract: two years;
- you will be classified as a Postdoctoral Researcher 4 in the Dutch university job-ranking system (UFO);
- you will be able to make use of our Dual Career Service where our Dual Career Officer will assist with family related support, such as child care, and help the partner of the candidate prepare for the local labour market and with finding an occupation.
Are you interested in our excellent employment conditions?
The Faculty of Science is an equal opportunity employer, committed to building a culturally diverse intellectual community, and as such encourages applications from women and minorities.
Would you like to know more?
For more information about this vacancy, please contact:
Prof. dr. Gert Jan C. Veenstra
Telephone: +31 24 3610541
Are you interested?
You should upload your application (attn. of prof. dr. Gert Jan C. Veenstra) exclusively using the button ‘Apply’ below. Your application should include (and be limited to) the following attachment(s):
- Motivation letter
- CV including the names of two references